Use of cognitive enhancers for mild cognitive impairment: protocol for a systematic review and network meta-analysis
نویسندگان
چکیده
منابع مشابه
Use of cognitive enhancers for mild cognitive impairment: protocol for a systematic review and network meta-analysis
BACKGROUND Elderly individuals who have memory problems without significant limitations in activities of daily living are often diagnosed as having mild cognitive impairment (MCI). Some of these individuals progress to dementia. Several cognitive enhancers (for example donepezil, galantamine, rivastigmine, memantine) have been approved for use in people with Alzheimer's dementia but their use i...
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BACKGROUND Approximately 35 million people world-wide have Alzheimer's disease and this is projected to nearly double by 2030. Cognitive enhancers, including cholinesterase inhibitors (for example, donepezil, galantamine and rivastigmine) and memantine (N-methyl-D-aspartic acid (NMDA) receptor antagonist) have been approved for the treatment of Alzheimer's disease in many countries. Our objecti...
متن کاملEfficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis.
BACKGROUND Cognitive enhancers, including cholinesterase inhibitors and memantine, are used to treat dementia, but their effectiveness for mild cognitive impairment is unclear. We conducted a systematic review to examine the efficacy and safety of cognitive enhancers for mild cognitive impairment. METHODS Our eligibility criteria were studies of the effects of donepezil, rivastigmine, galanta...
متن کاملTreatment for mild cognitive impairment: systematic review.
BACKGROUND More people are presenting with mild cognitive impairment (MCI), frequently a precursor to dementia, but we do not know how to reduce deterioration. AIMS To systematically review randomised controlled trials (RCTs) evaluating the effects of any intervention for MCI on cognitive, neuropsychiatric, functional, global outcomes, life quality or incident dementia. METHOD We reviewed 4...
متن کاملTreatment for mild cognitive impairment: a systematic review and meta-analysis.
BACKGROUND The effectiveness of treatments for mild cognitive impairment is uncertain. The aim of this review was to evaluate the effectiveness and harms of treatment for mild cognitive impairment in adults 65 years of age and older. METHODS We searched MEDLINE, Embase and Cochrane Central (December 2012-December 2014); citations from 2 systematic reviews were considered for inclusion. We inc...
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ژورنال
عنوان ژورنال: Systematic Reviews
سال: 2012
ISSN: 2046-4053
DOI: 10.1186/2046-4053-1-25